WebBackground: Calcium gluconate extravasation is a process that can cause serious lesions, such as necrosis and calcification of the soft tissues. The aim of the present study was to analyze the beneficial effects of four possible local antidotes for calcium gluconate extravasation: hyaluronidase, sodium thiosulfate, triamcinolone acetonide, and … Web14 aug. 2013 · Exposure to bacterial superantigens, such as staphylococcal enterotoxin B (SEB), can lead to the induction of acute lung injury/acute respiratory distress syndrome (ALI/ARDS). To date, there are no known effective treatments for SEB-induced inflammation. In the current study we investigated the potential use of the hyaluronic …
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Webrelief. Intradermal hyaluronidase has been effective for hyperosmotic extravasations, although its use lar-gely depends on the risk of tissue injury and the severity of extravasation. Among the hyperosmotic agents, calcium extravasation is distinctive because it may present as an acute tissue injury or may possess delayed clinical … WebThe medical treatment of extravasation is based on proper maintenance of the intravenous (IV) line and application of cold or warm compresses, plus the use of antidotes when available. Antidotes for extravasation that have been shown to be useful are sodium thiosulfate for nitrogen mustard, dimethylsulfoxide for anthracyclines and mitomycin, and … brown goo in utensils drawer
Extravasation injury from chemotherapy and other non
WebHyaluronidase is used as adjunct therapy to increase the absorption and dispersion of other injected drugs. The drug has also been used as an adjunct to nonpharmacologic management of extravasation of selected antineoplastic agents and other irritants. Web1 jul. 2013 · PURPOSE To describe the implementation and evaluation of an evidence-based guideline, Hyaluronidase for Treatment of IV Extravasations, in a pediatric population. CONCLUSIONS Evidence of hyaluronidase efficacy suggests that timely administration will decrease the severity of tissue damage caused by extravasations, and … WebGerhard Baumgartner, Gerhard Hamilton, in Hyaluronan in Cancer Biology, 2009. Publisher Summary. Hyaluronidase has been in clinical use involving chemotherapy for the treatment of extravasation in order to prevent tissue necrosis. A key event in alerting to the possible additional uses of hyaluronidase was the case of one myeloma patient who received a … eversley park centre