WebApr 6, 2024 · B Higher IRF1 expression is induced when LMeC cells are infected with rNDV-cIFN ... Using KMeC and LMeC cells, we studied IRF1 expression in rNDV-infected cells. The results showed that the expression of IRF genes increased in lymphocytes co-cultured with cells infected with rNDV-cIFNγ, which suggested that cIFNγ produced after recombinant ... WebNov 2, 2024 · Autophagy is an important factor in liver ischemia-reperfusion injury. In the current study we investigate the function of interferon regulatory factor-1 (IRF1) in regulating autophagy to promote hepatic ischemia reperfusion injury (IR). The high expression of IRF1 during hepatic IR exhibited increased liver damage and was associated with activation of …
IRF1 Inhibits Antitumor Immunity through the Upregulation of PD …
Web(A) The IRF1 expression in IRF1-knockout (IRF1-KO#1 and IRF1-KO#2) and parental wildtype (WT) HeLa cells was analyzed by Western blotting. ( B ) IRF1-knockout (IRF1-KO#1 and IRF1-KO#2) and parental (WT) HeLa cells were treated with 100 ng/mL IFNβ for 48 h, and then cells were replated in 96-well plates and treated with the indicated doses of ... WebJan 22, 2024 · To further prove whether IRF8/IRF1 bind to CASP1 promoter in B cells, we performed ChIP experiments using chromatin prepared from EBV-postive Akata, LCL and P3HR-1 cells. Our results showed that IRF8/IRF1 indeed bind to the promoter region of CASP1 for all these cells ( S5A Fig ), suggesting that they directly regulate CASP1 … iris usa weatherpro
Genetic defects of the IRF1-mediated major histocompatibility …
WebThe present findings suggest that IRF1 is associated with metastasis and the degree of immune infiltration of CD8+ T cells (general), dendritic cells, T-helper 1 cells, and T cell … WebSummary. Bat cells and tissue have elevated basal expression levels of antiviral genes commonly associated with interferon alpha (IFNα) signaling. Here, we show Interferon … WebNov 15, 2008 · Most importantly, IRF8 directly regulates the expression of EBF and PU.1, thereby defining novel aspects of the transcriptional regulatory network for specification … iris usa inc wire open pet pen